MR Spectroscopy in Multiple Sclerosis - A New Piece of the Puzzle or Just a New Puzzle
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چکیده
In the late ‘80s magnetic resonance imaging (MRI) and magnetic resonance spectroscopy (MRS) revolutionized the care and monitoring of patients with multiple sclerosis (MS). For the first time detailed, high resolution images of the brain, spinal cord and lesions could be made by MRI in vivo, and followed over time. However, the changes detectable on T1or T2-weighted magnetic resonance images are non-specific for the underlying pathology, especially in MS patients, and slow down the enthusiasm. They may reflect edema, demyelination, axonal loss, inflammation, gliosis, remyelination, or Wallerian degeneration in MS.
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تاریخ انتشار 2012